当前位置:首页>产品中心>单抗/多抗>Anti-Human BNC1 Polyclonal Antibody|抗人BNC1多克隆抗体(靶标:人锌指蛋白basonuclin-1)

Anti-Human BNC1 Polyclonal Antibody|抗人BNC1多克隆抗体(靶标:人锌指蛋白basonuclin-1)

  • 货号:RB9THD166014
  • 价格:面议
  • 点击:358

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标BNC, BNC1, Zinc finger protein basonuclin-1
免疫原E. coli - derived recombinant Human BNC1 (Thr38-Asn250).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q01954
背景信息

Zinc finger protein basonuclin-1 (BNC1) is a ~110 kDa protein. Transcriptional activator. It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles. Required for the maintenance of spermatogenesis. It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade. May also play a role in the early development of embryos.

1. Tseng, H. et al. (1994) The Journal of cell biology 126, 495-506. PMID: 8034748
2. Zhang, D. et al. (2018) Human molecular genetics 27, 3787-3800. PMID: 30010909
备注For research use only
【仅供科学研究使用】

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