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Anti-Human SOS2 Polyclonal Antibody|抗人SOS2多克隆抗体(靶标:人SOS Ras/Rac鸟苷酸交换因子2)

  • 货号:RB9THD170014
  • 价格:面议
  • 点击:562

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标SOS-2, SOS2, Son of sevenless homolog 2
免疫原E. coli - derived recombinant Human SOS2 (Met1-Asn561).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q07890
背景信息

Son of sevenless homolog 2 (SOS2) is a ~152 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RAS proteins. Catalyzes the GDP-to-GTP exchange, resulting in an increase of the active GTP-bound form of HRAS. Acts as a key modulator of PI3K-AKT signaling.

1. Liu, AM. et al. (2010) Cellular signalling 22, 1448-58. PMID: 20639119
备注For research use only
【仅供科学研究使用】

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