Anti-Human INCA1 Polyclonal Antibody|抗人INCA1多克隆抗体(靶标：人INCA1蛋白)
- 货号：RB9THD173014
- 价格：面议
- 点击：754
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | INCA1, Inhibitor of CDK interacting with cyclin A1, Protein INCA1 |
| 免疫原 | E. coli - derived recombinant Human INCA1 (Gln2-Glu236). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q0VD86 |
| 背景信息 | Protein INCA1 is a ~26 kDa protein. Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. 1. Bäumer, N. et al. (2011) The Journal of biological chemistry 286, 28210-22. PMID: 21540187 |
| 备注 | For research use only |
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