| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CAPD2, CNAP1, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, Condensin complex subunit 1, KIAA0159, NCAPD2, Non-SMC condensin I complex subunit D2, XCAP-D2 |
| 免疫原 | E. coli - derived recombinant Human NCAPD2 (Met1-Thr400). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q15021 |
| 背景信息 | Condensin complex subunit 1 (NCAPD2) is a ~157 kDa protein. Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. 1. Kimura, K. et al. (2001) The Journal of biological chemistry 276, 5417-20. PMID: 11136719 2. Martin, CA. et al. (2016) Genes & development 30, 2158-2172. PMID: 27737959 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6344 |
| 多菌灵/阿苯达唑二合一单抗 | 6422 |
| 三氯噻嗪单抗 | 6521 |
| 吡唑醚菌酯单抗 | 6758 |
| 烯酰吗啉单抗 | 6593 |
| 抑霉唑单抗 | 6282 |
| 恶醚唑(苯醚甲环唑)单抗 | 6449 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6474 |
| 辛硫磷单抗 | 6550 |
| 多效唑单抗 | 6430 |
| 对硫磷单抗 | 6628 |
| 丙溴磷单抗 | 6684 |
| 戊唑醇单抗 | 6681 |
| 莠去津单抗 | 6541 |
| 灭蝇胺单抗 | 6219 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6494 |
| 2.4-二氯苯氧乙酸单抗 | 6341 |
| 甲基对硫磷单抗 | 6417 |
| 左旋咪唑单抗 | 6366 |
| 三唑磷单抗 | 6450 |