Anti-Human TRMT5 Polyclonal Antibody|抗人TRMT5多克隆抗体(靶标：人tRNA甲基转移酶5)
- 货号：RB9THD270014
- 价格：面议
- 点击：598
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | EC:2.1.1.228, KIAA1393, M1G-methyltransferase, TRM5, TRMT5, tRNA (guanine(37)-N(1))-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog |
| 免疫原 | E. coli - derived recombinant Human TRMT5 (Thr65-Lys475). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q32P41 |
| 背景信息 | tRNA (guanine(37)-N(1))-methyltransferase (TRMT5) is a ~58 kDa protein. Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. 1. Powell, CA. et al. (2015) American journal of human genetics 97, 319-28. PMID: 26189817 |
| 备注 | For research use only |
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