Anti-Human TSHZ3 Polyclonal Antibody|抗人TSHZ3多克隆抗体(靶标：人Teashirt锌指同源盒蛋白3)
- 货号：RB9THD311014
- 价格：面议
- 点击：545
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | KIAA1474, TSH3, TSHZ3, Teashirt homolog 3, ZNF537, Zinc finger protein 537 |
| 免疫原 | E. coli - derived recombinant Human TSHZ3 (Trp898-Gln1081). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q63HK5 |
| 背景信息 | Teashirt homolog 3 (TSHZ3) is a ~118 kDa protein. Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. 1. Kajiwara, Y. et al. (2009) PloS one 4, e5071. PMID: 19343227 |
| 备注 | For research use only |
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