| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Alk-SMase, Alkaline sphingomyelin phosphodiesterase, E-NPP 7, EC:3.1.4.12, ENPP7, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, Intestinal alkaline sphingomyelinase, NPP-7 |
| 免疫原 | E. coli - derived recombinant Human ENPP7 (Asn31-Leu413). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q6UWV6 |
| 背景信息 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) is a ~51 kDa protein. Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract. Also has phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation. Does not have nucleotide pyrophosphatase activity. May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen. 1. Duan, RD. et al. (2003) Journal of lipid research 44, 1241-50. PMID: 12671034 2. Duan, RD. et al. (2003) The Journal of biological chemistry 278, 38528-36. PMID: 12885774 3. Wu, J. et al. (2004) American journal of physiology. Gastrointestinal and liver physiology 287, G967-73. PMID: 15205117 4. Wu, J. et al. (2006) The Biochemical journal 394, 299-308. PMID: 16255717 5. Gorelik, A. et al. (2017) The Journal of biological chemistry 292, 7087-7094. PMID: 28292932 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 过氧化物酶(HRP)标莱克多巴胺单克隆抗体 | 6700 |
| 过氧化物酶(HRP)标沙丁胺醇单克隆抗体 | 6809 |
| 呋喃唑酮代谢物(2-NPAOZ)单抗 | 7289 |
| 环丙沙星(CPFX)单抗 | 6726 |
| 氟喹诺酮类单抗 | 6779 |
| 恩诺沙星单抗 | 6691 |
| 环丙沙星|恩诺沙星|诺氟沙星三合一单抗 | 6641 |
| 睾酮单抗 | 6537 |
| 过氧化物酶(HRP)标睾酮单克隆抗体 | 6596 |
| 过氧化物酶(HRP)标雌三醇单克隆抗体 | 6968 |
| 过氧化物酶(HRP)标记甲基睾酮单克隆抗体 | 7127 |
| 黄曲霉毒素抗体(黄曲霉毒素B1,黄曲霉毒素总量单克隆抗体) | 6637 |
| 苏丹红1号单抗 | 6825 |
| 呋喃西林代谢物(2-NPSEM)单抗(40F11细胞株) | 6571 |
| 小鼠单克隆抗体Ig类/亚类鉴定ELISA试剂盒 | 7415 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定ELISA试剂盒 | 7635 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定酶标二抗即用套装 | 7562 |
| HRP标记小鼠单抗专用稀释液 | 7678 |
| 小鼠单抗腹水制备专用佐剂套装 | 7734 |
| 新冠病毒S蛋白中和抗体ELISA检测试剂盒 | 7314 |