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Anti-Human RADX Polyclonal Antibody|抗人RADX多克隆抗体(靶标:人RADX蛋白)

  • 货号:RB9THD368014
  • 价格:面议
  • 点击:652
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标CXorf57, RADX, RPA-related and RAD51-antagonist, X-chromosome, RPA-related protein RADX
免疫原E. coli - derived recombinant Human RADX (Ser44-Asn357).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q6NSI4
背景信息

RPA-related protein RADX is a ~97 kDa protein. Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks.

1. Dungrawala, H. et al. (2017) Molecular cell 67, 374-386.e5. PMID: 28735897
备注For research use only
【仅供科学研究使用】

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