当前位置:首页>产品中心>单抗/多抗>Anti-Mouse ATP6V0D2 Polyclonal Antibody|抗小鼠ATP6V0D2多克隆抗体(靶标:小鼠V型质子ATP酶d2亚基)

Anti-Mouse ATP6V0D2 Polyclonal Antibody|抗小鼠ATP6V0D2多克隆抗体(靶标:小鼠V型质子ATP酶d2亚基)

  • 货号:RB9TMD459014
  • 价格:面议
  • 点击:269
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse, Rat
靶标ATP6V0D2, V-ATPase subunit d 2, V-type proton ATPase subunit d 2, Vacuolar proton pump subunit d 2
免疫原E. coli - derived recombinant Mouse ATP6V0D2 (Met1-Leu350).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q80SY3
背景信息

V-type proton ATPase subunit d 2 (ATP6V0D2) is a ~40 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in coupling of proton transport and ATP hydrolysis. Regulator of osteoclast fusion and bone formation.

1. Nishi, T. et al. (2003) The Journal of biological chemistry 278, 46396-402. PMID: 12963731
2. Lee, SH. et al. (2006) Nature medicine 12, 1403-9. PMID: 17128270
备注For research use only
【仅供科学研究使用】

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