Anti-Human SVIL Polyclonal Antibody|抗人SVIL多克隆抗体(靶标：人Supervillin蛋白)
- 货号：RB9THF800014
- 价格：面议
- 点击：303
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | Archvillin, SVIL, Supervillin, p205/p250 |
| 免疫原 | E. coli - derived recombinant Human SVIL (Met1444-Lys1678). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O95425 |
| 背景信息 | Supervillin (SVIL) is a ~247 kDa protein. Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. 1. Oh, SW. et al. (2003) Journal of cell science 116, 2261-75. PMID: 12711699 2. Crowley, JL. et al. (2009) Molecular biology of the cell 20, 948-62. PMID: 19109420 3. Laurent, B. et al. (2015) Molecular cell 57, 957-970. PMID: 25684206 |
| 备注 | For research use only |
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