Anti-Human ACD Polyclonal Antibody|抗人ACD多克隆抗体(靶标：人肾上腺皮质发育不良蛋白/ACD)
- 货号：RB9THP465014
- 价格：面议
- 点击：358
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | ACD, Adrenocortical dysplasia protein homolog, PIP1, POT1 and TIN2-interacting protein, PTOP, TINT1, TPP1 |
| 免疫原 | E. coli - derived recombinant Human ACD (Ser24-Glu196). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q96AP0 |
| 背景信息 | Adrenocortical dysplasia protein homolog (ACD) is a ~48 kDa protein. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. |
| 备注 | For research use only |
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