| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DBR1, EC:3.1.4.-, Lariat debranching enzyme |
| 免疫原 | E. coli - derived recombinant Human DBR1 (Met1-Pro273). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UK59 |
| 背景信息 | Lariat debranching enzyme (DBR1) is a ~61 kDa protein. Cleaves the 2'-5' phosphodiester linkage at the branch point of excised lariat intron RNA and converts them into linear molecules that can be subsequently degraded, thereby facilitating ribonucleotide turnover. Linked to its role in pre-mRNA processing mechanism, may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis and have an antiviral cell-intrinsic defense function in the brainstem. 1. Kim, JW. et al. (2000) Nucleic acids research 28, 3666-73. PMID: 10982890 2. Ye, Y. et al. (2005) Retrovirology 2, 63. PMID: 16232320 3. Arenas, J. et al. (1987) The Journal of biological chemistry 262, 4274-9. PMID: 2435736 4. Zhang, SY. et al. (2018) Cell 172, 952-965.e18. PMID: 29474921 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| CA-125单克隆抗体 | 7069 |
| PSA单克隆抗体 | 7146 |
| AFP单克隆抗体 | 7135 |
| CA-724单克隆抗体 | 7020 |
| CA-199单克隆抗体 | 6962 |
| HE4单克隆抗体 | 6827 |
| 孕酮单克隆抗体 | 7446 |
| 人胎球蛋白A(Fetuin A)单克隆抗体 | 7160 |
| 胎盘泌乳素单克隆抗体 | 7092 |
| 泌乳素单克隆抗体 | 6765 |
| SP-10单克隆抗体 | 6998 |
| AMH单克隆抗体 | 7313 |
| 胎儿纤维链接蛋白单克隆抗体 | 7154 |
| HCG单克隆抗体 | 7059 |
| 人骨碱性磷酸酶单克隆抗体 | 6830 |
| 小分子单克隆抗体 | 7184 |
| 抗环瓜氨酸肽抗体(Anti-CCP)诊断试剂原料 | 7009 |
| 耐碳青霉烯单克隆抗体 | 7164 |
| 补体C4c单克隆抗体 | 7348 |
| 补体C3c单克隆抗体 | 6875 |