Anti-Mouse PLA2G1B Polyclonal Antibody|抗小鼠PLA2G1B多克隆抗体(靶标：小鼠磷脂酶A2-IB)
- 货号：RB9TMY504014
- 价格：面议
- 点击：913
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | EC:3.1.1.4, Group IB phospholipase A2, PLA2, PLA2A, PLA2G1B, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, Phospholipase A2 |
| 免疫原 | E. coli - derived recombinant Mouse PLA2G1B (Ser20-Cys146). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9Z0Y2 |
| 背景信息 | Phospholipase A2 (PLA2G1B) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines. May act in an autocrine and paracrine manner. 1. Cupillard, L. et al. (1999) The Journal of biological chemistry 274, 7043-51. PMID: 10066760 2. Entwistle, LJ. et al. (2017) Cell host & microbe 22, 484-493.e5. PMID: 29024642 |
| 备注 | For research use only |
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