Anti-Mouse FGA Polyclonal Antibody|抗小鼠FGA多克隆抗体(靶标：小鼠纤维蛋白原α链)
- 货号：RB9TMF809014
- 价格：面议
- 点击：593
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | Fga, Fibrinogen alpha chain, Fibrinopeptide A |
| 免疫原 | E. coli - derived recombinant Mouse FGA (Thr552-Gln789). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | E9PV24 |
| 背景信息 | Fibrinogen alpha chain (FGA) is a ~87 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. 1. Suh, TT. et al. (1995) Genes & development 9, 2020-33. PMID: 7649481 2. Drew, AF. et al. (2001) Blood 97, 3691-8. PMID: 11389004 3. Ni, H. et al. (2000) The Journal of clinical investigation 106, 385-92. PMID: 10930441 4. Yang, H. et al. (2009) Blood 114, 425-36. PMID: 19332769 5. Johnson, LL. et al. (2003) The Journal of experimental medicine 197, 801-6. PMID: 12629066 6. Luo, D. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4149-61. PMID: 23487423 |
| 备注 | For research use only |
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