| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Lymphocytic choriomeningitis virus |
| 靶标 | EC:2.7.7.48, EC:3.1.-.-, L, Large structural protein, Protein L, RNA-directed RNA polymerase L, Replicase, Transcriptase, cap-snatching endonuclease |
| 免疫原 | E. coli - derived recombinant LCMV RdRp/Protein L (Asp2-Lys196). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P14240 |
| 背景信息 | RNA-directed RNA polymerase L (RdRp/Protein L) is a ~254 kDa protein. RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped. 1. Liu, L. et al. (2023) Protein & cell 14, 703-707. PMID: 37038286 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 6679 |
| 西马特罗单抗 | 6843 |
| 孕酮单抗 | 6835 |
| 氯霉素(CAP)单抗 | 6918 |
| 红霉素单抗 | 6877 |
| 地克珠利单抗 | 6329 |
| 无色孔雀石绿(LMG)单抗 | 6583 |
| 雌二醇单抗 | 6620 |
| 孔雀石绿(MG)单抗 | 6787 |
| 双酚A单抗 | 6698 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 6541 |
| 己烯雌酚单抗 | 6669 |
| 莱克多巴胺(RAC)单抗 | 6776 |
| 林可霉素单抗 | 7879 |
| 抗青霉素受体单抗 | 6399 |
| 大观霉素单抗 | 6587 |
| 克伦特罗(CL)单抗 | 6785 |
| 沙拉沙星单抗(2H4) | 6744 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6602 |
| 磺胺类SAS单抗 | 6645 |