当前位置：首页>产品中心>单抗/多抗>Anti-HHV-5/HCMV UL83 Polyclonal Antibody|抗HHV-5/HCMV UL83多克隆抗体(靶标：人巨细胞病毒磷蛋白pp65/UL83)
Anti-HHV-5/HCMV UL83 Polyclonal Antibody|抗HHV-5/HCMV UL83多克隆抗体(靶标：人巨细胞病毒磷蛋白pp65/UL83)
- 货号：RB9TVK643014
- 价格：面议
- 点击：629
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human cytomegalovirus |
| 靶标 | 65 kDa matrix phosphoprotein, 65 kDa phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83, pp65 |
| 免疫原 | E. coli - derived recombinant HHV-5/HCMV UL83 (Thr297-Tyr510). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P06725 |
| 背景信息 | 65 kDa phosphoprotein (UL83) is a ~62 kDa protein. Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus. Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1. Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes. 1. Abate, DA. et al. (2004) Journal of virology 78, 10995-1006. PMID: 15452220 2. Biolatti, M. et al. (2018) Journal of virology 92. PMID: 29263269 3. Cox, JB. et al. (2025) Journal of virology 99, e0048125. PMID: 40243337 4. Cristea, IM. et al. (2010) Journal of virology 84, 7803-14. PMID: 20504932 |
| 备注 | For research use only |
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