| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human herpesvirus 2 |
| 靶标 | Envelope glycoprotein H, gH |
| 免疫原 | E. coli - derived recombinant HSV-2/HHV-2 glycoprotein H/gH (Arg49-Pro803). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P89445 |
| 背景信息 | Envelope glycoprotein H (gH) is a ~89 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interaction with host integrins ITGAV/ITGB3 triggers release of cytosolic Ca(2+) and FAK phosphorylation leading to efficient viral entry into host genital tract epithelial cells. 1. Cheshenko, N. et al. (2014) Journal of virology 88, 10026-38. PMID: 24942591 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| Trx鼠单抗标签 | 8117 |
| BrdU单抗 | 8102 |
| HRP-BrdU单抗 | 7819 |
| GAPDH 鼠单抗 | 7738 |
| HRP-GAPDH 鼠单抗 | 7726 |
| PCNA单抗 | 8268 |
| α-tubulin 鼠单抗 | 7697 |
| β-tubulin 鼠单抗 | 8221 |
| HRP-β-tubulin 鼠单抗 | 7993 |
| β-Actin 鼠单抗 | 8077 |
| HRP-β-Actin 鼠单抗 | 7668 |
| Histone H3鼠单抗 | 7840 |
| 糖基化血红蛋白单抗 | 8147 |
| 糖基化血红蛋白抗体 | 8010 |
| C肽鼠单抗 | 7298 |
| 胰岛素鼠单抗 | 7901 |
| 胃蛋白酶原II鼠单抗 | 8016 |
| 鼠抗人胃泌素17单抗 | 7772 |
| 心肌钙蛋白鼠单抗(CTNI抗体) | 7867 |
| 肌红蛋白鼠单抗 | 8039 |