Anti-Human SSB Polyclonal Antibody|抗人SSB多克隆抗体(靶标：人干燥综合征抗原B/La蛋白)
- 货号：RB9THY125014
- 价格：面议
- 点击：960
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | La autoantigen, La ribonucleoprotein, Lupus La protein, SS-B, SSB, Sjoegren syndrome type B antigen |
| 免疫原 | E. coli - derived recombinant Human SSB (Ala2-Lys185). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P05455 |
| 背景信息 | Lupus La protein (SSB) is a ~46 kDa protein. Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. 1. Gottlieb, E. et al. (1989) The EMBO journal 8, 851-61. PMID: 2470590 2. Chambers, JC. et al. (1988) The Journal of biological chemistry 263, 18043-51. PMID: 3192525 3. Ray, PS. et al. (2002) Nucleic acids research 30, 4500-8. PMID: 12384597 |
| 备注 | For research use only |
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