| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | C9orf2, H7365, TMEFF1, TR-1, Tomoregulin-1, Transmembrane protein with EGF-like and one follistatin-like domain |
| 免疫原 | E. coli - derived recombinant Human TMEFF1 (Gly86-Glu302). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8IYR6 |
| 背景信息 | Tomoregulin-1 (TMEFF1) is a ~40 kDa protein. Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers. 1. Dai, Y. et al. (2024) Nature 632, 383-389. PMID: 39048823 2. Chan, YH. et al. (2024) Nature 632, 390-400. PMID: 39048830 3. Gery, S. et al. (2003) Oncogene 22, 2723-7. PMID: 12743596 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 7793 |
| 多菌灵/阿苯达唑二合一单抗 | 7705 |
| 三氯噻嗪单抗 | 7810 |
| 吡唑醚菌酯单抗 | 8951 |
| 烯酰吗啉单抗 | 9281 |
| 抑霉唑单抗 | 7857 |
| 恶醚唑(苯醚甲环唑)单抗 | 7793 |
| 赛拉嗪(甲苯噻嗪)单抗 | 7614 |
| 辛硫磷单抗 | 7772 |
| 多效唑单抗 | 8637 |
| 对硫磷单抗 | 8857 |
| 丙溴磷单抗 | 8437 |
| 戊唑醇单抗 | 8527 |
| 莠去津单抗 | 8186 |
| 灭蝇胺单抗 | 8069 |
| 尼卡巴嗪代谢物(DNC)单抗 | 7904 |
| 2.4-二氯苯氧乙酸单抗 | 7568 |
| 甲基对硫磷单抗 | 7491 |
| 左旋咪唑单抗 | 8163 |
| 三唑磷单抗 | 8302 |