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Anti-Human F7 Polyclonal Antibody|抗人F7多克隆抗体(靶标:人凝血因子VII)

  • 货号:RB9THY060024
  • 价格:面议
  • 点击:771
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标Coagulation factor VII, EC:3.4.21.21, Eptacog alfa, F7, Factor VII heavy chain, Factor VII light chain, Proconvertin, SPCA, Serum prothrombin conversion accelerator
免疫原E. coli - derived recombinant Human F7 (Ile213-Pro466).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P08709
背景信息

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951
备注For research use only
【仅供科学研究使用】

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