| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | C2, C3/C5 convertase, Complement C2, Complement C2a, EC:3.4.21.43, Serine protease complement C2b |
| 免疫原 | E. coli - derived recombinant Human C2 (Ile245-His451). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P06681 |
| 背景信息 | Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 6626 |
| 西马特罗单抗 | 6771 |
| 孕酮单抗 | 6784 |
| 氯霉素(CAP)单抗 | 6838 |
| 红霉素单抗 | 6788 |
| 地克珠利单抗 | 6287 |
| 无色孔雀石绿(LMG)单抗 | 6527 |
| 雌二醇单抗 | 6545 |
| 孔雀石绿(MG)单抗 | 6732 |
| 双酚A单抗 | 6639 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 6461 |
| 己烯雌酚单抗 | 6587 |
| 莱克多巴胺(RAC)单抗 | 6734 |
| 林可霉素单抗 | 7748 |
| 抗青霉素受体单抗 | 6350 |
| 大观霉素单抗 | 6532 |
| 克伦特罗(CL)单抗 | 6729 |
| 沙拉沙星单抗(2H4) | 6685 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6581 |
| 磺胺类SAS单抗 | 6611 |