| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | ALCAM, Activated leukocyte cell adhesion molecule, CD166, CD166 antigen, MEMD |
| 免疫原 | E. coli - derived recombinant Human CD166/ALCAM (Trp28-Lys527). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13740 |
| 背景信息 | CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation. 1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703 2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415 3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806 4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771 5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728 6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007 7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938 8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 7230 |
| 多菌灵/阿苯达唑二合一单抗 | 7254 |
| 三氯噻嗪单抗 | 7268 |
| 吡唑醚菌酯单抗 | 8095 |
| 烯酰吗啉单抗 | 8275 |
| 抑霉唑单抗 | 7228 |
| 恶醚唑(苯醚甲环唑)单抗 | 7279 |
| 赛拉嗪(甲苯噻嗪)单抗 | 7186 |
| 辛硫磷单抗 | 7281 |
| 多效唑单抗 | 7773 |
| 对硫磷单抗 | 7989 |
| 丙溴磷单抗 | 7760 |
| 戊唑醇单抗 | 7819 |
| 莠去津单抗 | 7535 |
| 灭蝇胺单抗 | 7351 |
| 尼卡巴嗪代谢物(DNC)单抗 | 7373 |
| 2.4-二氯苯氧乙酸单抗 | 7060 |
| 甲基对硫磷单抗 | 7085 |
| 左旋咪唑单抗 | 7464 |
| 三唑磷单抗 | 7623 |