Anti-Human PPP1R11 Polyclonal Antibody|抗人PPP1R11多克隆抗体(靶标：人蛋白磷酸酶1调节亚基11)
- 货号：RB9THD625014
- 价格：面议
- 点击：788
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat |
| 靶标 | E3 ubiquitin-protein ligase PPP1R11, EC:2.3.2.27, HCG V, HCGV, Hemochromatosis candidate gene V protein, PPP1R11, Protein phosphatase 1 regulatory subunit 11, Protein phosphatase inhibitor 3, TCTE5 |
| 免疫原 | E. coli - derived recombinant Human PPP1R11 (Arg26-His126). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O60927 |
| 背景信息 | E3 ubiquitin-protein ligase PPP1R11 is a ~13 kDa protein. Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. 1. McKelvey, AC. et al. (2016) eLife 5. PMID: 27805901 2. Zhang, J. et al. (1998) Biochemistry 37, 16728-34. PMID: 9843442 |
| 备注 | For research use only |
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