Anti-Human AGTR2 Polyclonal Antibody|抗人AGTR2多克隆抗体(靶标：人血管紧张素Ⅱ受体2型)
- 货号：RB9THW681014
- 价格：面议
- 点击：691
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | AGTR2, AT2 receptor, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor |
| 免疫原 | E. coli - derived recombinant Human AGTR2 (Lys2-Asp45&Arg182-Gln206&Val321-Ser363). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P50052 |
| 背景信息 | Type-2 angiotensin II receptor (AGTR2) is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. 1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944 2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536 3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086 4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599 5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706 |
| 备注 | For research use only |
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