Anti-Human CMKLR2 Polyclonal Antibody|抗人CMKLR2多克隆抗体(靶标：人趋化因子样受体2)
- 货号：RB9THD623014
- 价格：面议
- 点击：824
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | CMKLR2, Chemerin chemokine-like receptor 2, Chemerin-like receptor 2, Chemokine-like receptor 2, G-protein coupled receptor 1, GPR1 |
| 免疫原 | E. coli - derived recombinant Human CMKLR2 (Glu2-Ser41&Ser308-Gln355). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P46091 |
| 背景信息 | Chemerin-like receptor 2 (CMKLR2) is a ~41 kDa protein. Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Also acts as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway. 1. Barnea, G. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 64-9. PMID: 18165312 2. De Henau, O. et al. (2016) PloS one 11, e0164179. PMID: 27716822 |
| 备注 | For research use only |
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