Anti-Human SOX11 Polyclonal Antibody|抗人SOX11多克隆抗体(靶标：人SRY相关HMG盒转录因子11)
- 货号：RB9THD615014
- 价格：面议
- 点击：559
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | SOX11, Transcription factor SOX-11 |
| 免疫原 | E. coli - derived recombinant Human SOX11 (Asn54-Tyr113). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P35716 |
| 背景信息 | Transcription factor SOX-11 (SOX11) is a ~46 kDa protein. Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. 1. Tsurusaki, Y. et al. (2014) Nature communications 5, 4011. PMID: 24886874 2. Hempel, A. et al. (2016) Journal of medical genetics 53, 152-62. PMID: 26543203 |
| 备注 | For research use only |
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