Anti-Human AHI1 Polyclonal Antibody|抗人AHI1多克隆抗体(靶标：人Abelson辅助整合位点1)
- 货号：RB9THV430014
- 价格：面议
- 点击：744
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | AHI-1, AHI1, Abelson helper integration site 1 protein homolog, Jouberin |
| 免疫原 | E. coli - derived recombinant Human AHI1 (Arg596-Ile917). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8N157 |
| 背景信息 | Jouberin (AHI1) is a ~137 kDa protein. Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. 1. Lancaster, MA. et al. (2011) Nature medicine 17, 726-31. PMID: 21623382 |
| 备注 | For research use only |
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