Anti-Human PRC1 Polyclonal Antibody|抗人PRC1多克隆抗体(靶标：人胞质分裂调节蛋白1)
- 货号：RB9THD582014
- 价格：面议
- 点击：458
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | PRC1, Protein regulator of cytokinesis 1 |
| 免疫原 | E. coli - derived recombinant Human PRC1 (Met1-Ser466). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O43663 |
| 背景信息 | Protein regulator of cytokinesis 1 (PRC1) is a ~71 kDa protein. Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. 1. Kanehira, M. et al. (2007) Cancer research 67, 3276-85. PMID: 17409436 |
| 备注 | For research use only |
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