Anti-Human CEMIP Polyclonal Antibody|抗人CEMIP多克隆抗体(靶标：人细胞迁移诱导透明质酸结合蛋白)
- 货号：RB9THV103044
- 价格：面议
- 点击：714
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CEMIP, Cell migration-inducing and hyaluronan-binding protein, EC:3.2.1.35, HYBID, Hyaluronan binding protein involved in hyaluronan depolymerization, KIAA1199 |
| 免疫原 | E. coli - derived recombinant Human CEMIP (Thr31-Ala386). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8WUJ3 |
| 背景信息 | Cell migration-inducing and hyaluronan-binding protein (CEMIP) is a ~152 kDa protein. Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. |
| 备注 | For research use only |
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