当前位置:首页>产品中心>单抗/多抗>Anti-Human MBP Polyclonal Antibody|抗人MBP多克隆抗体(靶标:人髓鞘碱性蛋白)

Anti-Human MBP Polyclonal Antibody|抗人MBP多克隆抗体(靶标:人髓鞘碱性蛋白)

  • 货号:RB9THF789014
  • 价格:面议
  • 点击:528
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Rat
靶标MBP, Myelin A1 protein, Myelin basic protein, Myelin membrane encephalitogenic protein
免疫原E. coli - derived recombinant Human MBP (Met1-Lys192).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P02686
背景信息

Myelin basic protein (MBP) is a ~33 kDa protein. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.

备注For research use only
【仅供科学研究使用】

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