Anti-Human RIOK1 Polyclonal Antibody|抗人RIOK1多克隆抗体(靶标：人RIO激酶1)
- 货号：RB9THV201014
- 价格：面议
- 点击：579
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | EC:2.7.11.1, EC:3.6.1.-, RIO kinase 1, RIO1, RIOK1, Serine/threonine-protein kinase RIO1 |
| 免疫原 | E. coli - derived recombinant Human RIOK1 (Thr180-Val479). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9BRS2 |
| 背景信息 | Serine/threonine-protein kinase RIO1 (RIOK1) is a ~65 kDa protein. Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. 1. Widmann, B. et al. (2012) Molecular biology of the cell 23, 22-35. PMID: 22072790 2. Guderian, G. et al. (2011) The Journal of biological chemistry 286, 1976-86. PMID: 21081503 |
| 备注 | For research use only |
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