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Anti-Human SCNN1D Polyclonal Antibody|抗人SCNN1D多克隆抗体(靶标:人钠通道上皮1δ亚基)

  • 货号:RB9THD658014
  • 价格:面议
  • 点击:563
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标Amiloride-sensitive sodium channel subunit delta, DNACH, Delta-ENaC, Delta-NaCH, ENaCD, Epithelial Na(+) channel subunit delta, Epithelial sodium channel subunit delta, Nonvoltage-gated sodium channel
免疫原E. coli - derived recombinant Human SCNN1D (Arg277-Tyr683).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P51172
背景信息

Epithelial sodium channel subunit delta (SCNN1D) is a ~87 kDa protein. Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels.

1. Ji, HL. et al. (2006) The Journal of biological chemistry 281, 8233-41. PMID: 16423824
2. Bangel-Ruland, N. et al. (2010) American journal of respiratory cell and molecular biology 42, 498-505. PMID: 19520916
3. Zhao, RZ. et al. (2012) American journal of physiology. Lung cellular and molecular physiology 302, L1262-72. PMID: 22505667
4. Waldmann, R. et al. (1995) The Journal of biological chemistry 270, 27411-4. PMID: 7499195
备注For research use only
【仅供科学研究使用】

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