| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 9246 |
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| 肝素结合蛋白单克隆抗体 | 8781 |
| CRP单克隆抗体 | 10250 |
| 猫胰脂肪酶单克隆抗体 | 8632 |
| 马SAA单克隆抗体 | 10459 |
| 犬腺病毒单克隆抗体 | 8404 |
| 犬轮状病毒单克隆抗体 | 8475 |
| 犬血红蛋白单克隆抗体 | 10119 |
| 犬胰脂肪酶单克隆抗体 | 8148 |
| 犬松弛素单克隆抗体 | 8663 |
| 犬冠状病毒单克隆抗体 | 8528 |
| 犬瘟病毒单克隆抗体 | 8367 |
| 犬细小病毒单克隆抗体 | 9204 |
| 猫瘟病毒单克隆抗体 | 9437 |
| 猫疱疹病毒单克隆抗体 | 8762 |
| 猫杯状病毒单克隆抗体 | 9775 |
| 猫SAA单克隆抗体 | 8885 |
| 犬CRP单克隆抗体 | 9519 |
| 犬、猫IgG单克隆抗体 | 8597 |