| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 6661 |
| 西马特罗单抗 | 6813 |
| 孕酮单抗 | 6817 |
| 氯霉素(CAP)单抗 | 6875 |
| 红霉素单抗 | 6834 |
| 地克珠利单抗 | 6313 |
| 无色孔雀石绿(LMG)单抗 | 6551 |
| 雌二醇单抗 | 6593 |
| 孔雀石绿(MG)单抗 | 6757 |
| 双酚A单抗 | 6664 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 6496 |
| 己烯雌酚单抗 | 6623 |
| 莱克多巴胺(RAC)单抗 | 6769 |
| 林可霉素单抗 | 7826 |
| 抗青霉素受体单抗 | 6377 |
| 大观霉素单抗 | 6569 |
| 克伦特罗(CL)单抗 | 6756 |
| 沙拉沙星单抗(2H4) | 6726 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6592 |
| 磺胺类SAS单抗 | 6637 |