| 产品描述 | The MAR1-5A3 monoclonal antibody recognizes mouse IFNAR-1, one of the two subunits (with IFNAR-2) that form the Type I interferon receptor complex expressed on most cells. This receptor mediates IFN-α/β–driven antiviral, antimicrobial, antitumor, and immunoregulatory responses, influencing activation, proliferation, and differentiation across diverse cell types. MAR1-5A3 effectively blocks Type I IFN receptor signaling in vitro and in vivo. |
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| 形态 | Liquid |
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| 宿主种属 | Rat |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG1, kappa |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 内毒素水平 | <1 EU/mg |
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| 应用 | in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade, WB |
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| 种属反应性 | Mouse |
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| 靶标 | Interferon alpha/beta receptor 1, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, IFN-R-1, IFNAR1, IFNAR, IFN-alpha/beta receptor 1, Type I interferon receptor 1 |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
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| 登录号 | P33896 |
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| 备注 | For research use only. |
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