| 形态 | Liquid |
|---|
| 宿主种属 | Rabbit |
|---|
| 克隆性 | Polyclonal |
|---|
| 抗体亚型 | IgG |
|---|
| 纯化方式 | Purified by antigen affinity column. |
|---|
| 内毒素水平 | Please contact with the lab for this information. |
|---|
| 应用 | ELISA |
|---|
| 特异性 | The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays. |
|---|
| 免疫原 | Ramucirumab |
|---|
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
|---|
| 稳定性和储存 | The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
|---|
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
|---|
| 登录号 | CAS: 947687-13-0 |
|---|
| 背景信息 | Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells. |
|---|
| 别名 | Rabbit polyclonal to REGN-10987. |
|---|
| 备注 | For research use only. |
|---|