| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA |
| 特异性 | The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays. |
| 靶标 | Rabbit polyclonal to Soliris. |
| 免疫原 | Eculizumab |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 稳定性和储存 | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | CAS: 219685-50-4 |
| 背景信息 | Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions. • Induction Immunosuppression in High-risk Kidney Transplant Recipients., PMID:27041548 • Acute Rejection Following Kidney Transplantation: State-of-the-Art and Future Perspectives., PMID:32520680 • The impact of terminal complement blockade on the efficacy of induction with polyclonal rabbit antithymocyte globulin in living donor renal allografts., PMID:22813834 |
| 备注 | For research use only. |
| 产品名称 | 点击数 |
|---|---|
| 通用型抗体标记物保存液 | 6372 |
| HRP标记抗体保存液 | 6624 |
| Biotin标记抗体保存液 | 6865 |
| FITC标记抗体保存液 | 6530 |
| Myc鼠单抗标签 | 6596 |
| HRP-Myc鼠单抗标签 | 6641 |
| Flag鼠单抗标签 | 7032 |
| HRP-Flag鼠单抗标签 | 6741 |
| GFP鼠单抗标签 | 6717 |
| HRP-GFP鼠单抗标签 | 6524 |
| GST鼠单抗标签 | 6618 |
| HRP-GST鼠单抗标签 | 6584 |
| HA鼠单抗标签 | 6942 |
| HRP-HA鼠单抗标签 | 6783 |
| His鼠单抗标签 | 6620 |
| HRP-His鼠单抗标签 | 6602 |
| MBP鼠单抗标签 | 6486 |
| HRP-MBP鼠单抗标签 | 6850 |
| mCherry鼠单抗标签 | 6402 |
| RFP-鼠单抗标签 | 6637 |