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Anti-Panitumumab Polyclonal Antibody|抗帕尼单抗多克隆抗体(靶标:帕尼单抗(抗EGFR单抗))

  • 货号:RB9TAF004024
  • 价格:面议
  • 点击:235

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA
特异性The product is specific for Panitumumab. This antibody serves as an excellent positive control for Panitumumabb immunogenicity (ADA) assays.
靶标Rabbit polyclonal to Vectibix.
免疫原Panitumumab
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号CAS: 339177-26-3
背景信息Panitumumab with trade name Vectibix, is an FDA-approved drug for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma with non-mutated (wild-type) KRAS after failure of fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens. It is a human monoclonal antibody. Panitumumab binds to the human EGF receptor (EGFR), preventing binding of activating ligands, such as the EGF and transforming growth factor-α. Antibodysystem Anti-Panitumumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Panitumumab.
• Multiplexed evaluation of a cell-based assay for the detection of antidrug neutralizing antibodies to panitumumab in human serum using automated fluorescent microscopy., PMID:20508254
备注For research use only.
【仅供科学研究使用】

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