Anti-Human IL-1 beta/IL-1F2 Reference Antibody|抗人IL-1β/IL-1F2参考抗体(靶标：人白细胞介素-1β)
- 货号：RB9THF943026
- 价格：面议
- 点击：209
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1.31 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 表达系统 | Mammalian Cells |
| 登录号 | P01584 |
| 背景信息 | Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes. • Understanding the mechanism of IL-1β secretion., PMID:22019906 • NLRP3 inflammasome mediates M1 macrophage polarization and IL-1β production in inflammatory root resorption., PMID:31976565 • The role of IL-1β and TNF-α in intervertebral disc degeneration., PMID:32853910 • Human Monocytes Engage an Alternative Inflammasome Pathway., PMID:27037191 • D-mannose suppresses macrophage IL-1β production., PMID:33311467 • BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity., PMID:29324233 • Association of interleukin-6 and interleukin-1-β levels in patients with toxoplasmosis., PMID:35782407 • Interleukin-1 beta is significantly upregulated in the decidua of spontaneous and recurrent miscarriage placentas., PMID:33545613 • The effect of interleukin 1 beta blockade on the tumor microenvironment., PMID:33493144 • Single-cell profiling identifies IL1Bhi macrophages associated with inflammation in PD-1 inhibitor-induced inflammatory arthritis., PMID:38453911 |
| 别名 | XOMA 052, 1129435-60-4 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5532 |
| 金刚烷胺单抗 | 5591 |
| 卡那霉素单抗 | 5745 |
| 黄曲霉毒素M1（AFM1）单抗 | 5699 |
| 群勃龙（孕三烯酮）（去甲雄三烯醇酮）单抗 | 5901 |
| 帕托珠利（妥曲珠利砜）单抗 | 5605 |
| 泰乐菌素单抗 | 5657 |
| 替米考星单抗 | 5779 |
| 新霉素单抗 | 5754 |
| 安普霉素单抗 | 5701 |
| 三聚氰胺（MEL）单抗 | 5606 |
| 双氟沙星单抗 | 5558 |
| 西地那非单抗 | 5674 |
| 阿苯达唑单抗 | 5464 |
| 醋酸甲羟孕酮（醋酸甲孕酮）单抗 | 5637 |
| 氟苯尼考单抗 | 5666 |
| 诺龙单抗 | 5742 |
| 达氟沙星单抗 | 5865 |
| 培氟沙星单抗 | 5721 |
| 庆大霉素单抗 | 5868 |