Anti-Digoxin Recombinant Antibody|抗地高辛重组抗体(靶标：地高辛)
- 货号：RB9TYP336013
- 价格：面议
- 点击：443
产品介绍
产品参数
| 产品描述 | The antibody is specific for digoxin, a cardiac glycoside derived from the foxglove plant. Digoxin is administered for the therapeutic treatment of heart conditions such as atrial fibrillation, atrial flutter and heart failure, an acts by inhibiting the Na+/K+ ATPase. However, the drug has a very narrow therapeutic index and can cause toxic side effects. The Fab fragment prepared from 26-10 that neutralises the activity of digoxin and can be used as an antidote in case of overdose of digitalis. Anti-digoxin monoclonal antibodies can also be used to measure serum levels of the drug as a guide to therapy, and are useful in the investigation of the kinetics of interaction between antibody and antigen. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2a, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | CLIA, DB, ELISA, IP, RIA, WB |
| 靶标 | Digoxin, DGX, 20830-75-5, digoxinum, 12β-hydroxydigitoxin, ChEBI: 4551, 26-10#, 26G10 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000; WB: 1:500-1:2000 |
| 备注 | For research use only. |
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