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Recombinant Rhesus Macaque B7-H4 (C-Fc)

  • 货号:EPT264
  • 价格:¥5,280.00 元
  • 点击:1640

产品介绍

基本信息

规格50ug
表达宿主Human Cells
标签C-Fc

物理性质

分子量52.5 KDa
表观分子量70-100 KDa, reducing conditions
形态Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

溶解方法Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
储存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
【仅供科学研究使用】

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