Recombinant Human TPBG (C-6His)

产品介绍

{"gui_ge":"50ug","biao_da_su_zhu":"Human Cells","biao_qian":"C-6His","fen_zi_liang":"36.1 KDa","biao_guan_fen_zi_liang":"55-80 KDa, reducing conditions","xing_tai":"Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 .","chun_du":"Greater than 95% as determined by reducing SDS-PAGE.","nei_du_su_shui_ping":"Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.","rong_jie_fang_fa":"Always centrifuge tubes before opening.Do not mix by vortex or pipetting.\nIt is not recommended to reconstitute to a concentration less than 100μg\/ml.\nDissolve the lyophilized protein in distilled water.\nPlease aliquot the reconstituted solution to minimize freeze-thaw cycles. ","chu_cun_fang_fa":"Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.\nReconstituted protein solution can be stored at 4-7°C for 2-7 days.\nAliquots of reconstituted samples are stable at < -20°C for 3 months.","yun_shu_tiao_jian":"The product is shipped at ambient temperature.\nUpon receipt, store it immediately at the temperature listed below.","bei_jing_shuo_ming":"Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt\/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma."}