Recombinant Mouse IL-23
- 货号：EPT183
- 价格：￥2,160.00 元
- 点击：705
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | Human Cells |
| 标签 | NA |
物理性质
| 分子量 | 19.7&35.8 KDa |
|---|---|
| 表观分子量 | 18&40-55 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
|---|---|
| 活性 | Measured by its ability to induce STAT reporter activity in 293F human embryonic kidney cells.The ED50 for this effect is 501.08 ng/ml. |
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| HRP标记物工作稀释液(含BSA通用型) | 4959 |
| FITC牛血清白蛋白BSA | 4843 |
| C肽抗原 | 5049 |
| 胰岛素抗原 | 4881 |
| 抗环瓜氨酸肽抗原(CCP-A) | 4903 |
| 抗环瓜氨酸肽抗原(CCP-B) | 4823 |
| 抗环瓜氨酸肽抗原(CCP-C) | 5008 |
| 二十五羟基维生素D3偶联BSA抗原 | 5469 |
| MEL-BSA | 4996 |
| 纳他霉素-BSA | 5143 |
| 孔雀石绿-BSA | 4886 |
| 隐性孔雀石绿-BSA | 5026 |
| 微囊藻毒素LR-BSA | 4956 |
| 黄曲霉B1-BSA | 4949 |
| 黄曲霉M1-BSA | 4963 |
| T2-BSA | 4886 |
| 赭曲霉毒素(OTA)-BSA | 5178 |
| ZEN-BSA | 5149 |
| DON-BSA | 4970 |
| 伏马毒素-BSA | 5014 |