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Recombinant Rat M-CSF

  • 货号:EPT130
  • 价格:¥1,800.00 元
  • 点击:1246
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产品介绍

基本信息

规格10ug
表达宿主Human Cells
标签NA

物理性质

分子量25.2 KDa
表观分子量46 KDa, reducing conditions
形态Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

溶解方法Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
储存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
【仅供科学研究使用】

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