Recombinant Mouse FGFb
- 货号：EPT120
- 价格：￥1,680.00 元
- 点击：579
产品介绍
基本信息
| 规格 | 50ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 17.15 KDa |
|---|---|
| 表观分子量 | 16 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 400mM NaCl, 0.02% Tween 80, 4.0% Sucrose, 4.0% Manntiol, pH 7.0. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysaccharides and lipids with lower affinity. Expression of FGF basic is nearly ubiquitous but disruption of the mouse FGF basic gene gives a relatively mild phenotype, suggesting compensation by other FGF family members. FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis is reminiscent of a variety of pathological conditions. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| HDV 丁肝 | 1719 |
| 伤寒抗原 | 1515 |
| Syphilis 梅毒抗原抗体 | 1589 |
| A型产气荚膜梭菌a毒素蛋白 | 1525 |
| Clonorchiasis 肝吸虫 | 1354 |
| Schistosoma 血吸虫 | 1398 |
| β内酰胺受体 | 1350 |
| cProg犬孕酮 | 1469 |
| 犬钩端螺旋体抗原 | 1959 |
| 弓形虫抗原 | 1968 |
| FHV-I猫疱疹I型抗原 | 2145 |
| FIV猫艾滋抗原 | 2086 |
| 包虫 | 2207 |
| 犬瘟热重组抗原 Canine Distemper Virus Antigen | 1152 |
| Recombinant Human IGFBP-5 (C-6His) | 400 |
| Recombinant 2019-nCoV NSP10 (N-6His) | 382 |
| Recombinant 2019-nCoV Guanine-N7_meth (N-6His) | 443 |
| Recombinant Human EGF | 835 |
| Recombinant Human TGF-beta 1 | 850 |
| Anti-2019-nCoV S-IgM Neutralizing Antibody (8A5) | 655 |