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Recombinant Human IL-1b

  • 货号:EPT039
  • 价格:¥1,260.00 元
  • 点击:971

产品介绍

基本信息

规格10ug
表达宿主E.coli
标签NA

物理性质

分子量17.5 KDa
表观分子量17 KDa, reducing conditions
形态Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
活性Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells(Cat#XCC10). The ED50 for this effect is 20-100 pg/ml.

储存与运输

储存方法Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
运输条件The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
【仅供科学研究使用】

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