Recombinant Human IL-15
- 货号：EPT012
- 价格：￥5,280.00 元
- 点击：805
产品介绍
基本信息
| 规格 | 50ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 12.5 KDa |
|---|---|
| 表观分子量 | 12 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|---|
| 活性 | Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 40-200pg/ml. |
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 杀螟硫磷-BSA（或OVA）抗原 | 3872 |
| 二嗪磷-BSA（或OVA）抗原 | 3927 |
| 甲基对硫磷-BSA（或OVA）抗原 | 4004 |
| 氯苯那敏-BSA（或OVA）抗原 | 4037 |
| 水胺硫磷-BSA（或OVA抗原） | 3869 |
| 泰拉霉素-BSA（或OVA）抗原 | 3971 |
| 二甲戊灵-BSA（或OVA）抗原 | 4084 |
| 腐霉利-BSA（或OVA）抗原 | 3901 |
| 甲基睾酮-BSA（或OVA）抗原 | 3972 |
| 醋酸美伦孕酮-BSA（或OVA）抗原 | 3960 |
| 硝呋烯腙-BSA（或OVA）抗原 | 3945 |
| 倍他米松-BSA（或OVA）抗原 | 4081 |
| 福莫特罗-BSA（或OVA）抗原 | 3769 |
| 替硝唑-BSA（或OVA）抗原 | 3922 |
| 布洛芬-BSA（或OVA）抗原 | 3943 |
| 地昔尼尔-BSA（或OVA）抗原 | 3919 |
| 2,4,5-三氯苯氧乙酸-BSA（或OVA）抗原 | 4043 |
| 4-氯苯氧乙酸-BSA（或OVA）抗原 | 3850 |
| 赤霉素-BSA（或OVA）抗原 | 4024 |
| 6-苄氨基嘌呤-BSA（或OVA）抗原 | 3827 |