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Recombinant K. pneumoniae NEO

  • 货号:EPT008
  • 价格:¥3,780.00 元
  • 点击:832

产品介绍

基本信息

规格50ug
表达宿主E.coli
标签NA

物理性质

分子量29 KDa
表观分子量26-30 KDa, reducing conditions
形态Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

储存方法Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
运输条件The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
【仅供科学研究使用】

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