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Recombinant 2019-nCoV Guanine-N7_meth (N-6His)

  • 货号:EPT003
  • 价格:¥5,400.00 元
  • 点击:1041

产品介绍

基本信息

规格50ug
表达宿主E.coli
标签N-6His

物理性质

分子量62.9 KDa
表观分子量60 KDa, reducing conditions
形态Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
纯度Greater than 85% as determined by reducing SDS-PAGE.

储存与运输

储存方法Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
运输条件The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14.
【仅供科学研究使用】

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