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Recombinant 2019-nCoV NSP10 (N-6His)

  • 货号:EPT002
  • 价格:¥5,400.00 元
  • 点击:993
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产品介绍

基本信息

规格50ug
表达宿主E.coli
标签N-6His

物理性质

分子量17.9 KDa
表观分子量18 KDa, reducing conditions
形态Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
纯度Greater than 80% as determined by reducing SDS-PAGE.

储存与运输

储存方法Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
运输条件The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.
【仅供科学研究使用】

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